In a 4-year randomized control trial published in the Annals of Internal Medicine, 2009, Esposito and Colleagues compared the effects of a low-carbohydrate Mediterranean diet (LCMD) (less than 50 percent carbohydrate) to a typical low-fat diet (LF) (less than 30 percent fat) on the need for antihyperglycemic medication in patients with newly diagnosed type 2 diabetes.
